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Nb-Ti-Zr alloys for orthopedic implants
Journal of Biomaterials Applications ( IF 2.9 ) Pub Date : 2020-11-04 , DOI: 10.1177/0885328220970756
Taomei Zhang 1 , Pinghua Ou 1 , Jianming Ruan 1 , Hailin Yang 1
Affiliation  

Niobium (Nb), Titanium (Ti), and Zirconium (Zr) have attracted much attention as implant materials due to it’s excellent mechanical properties and biocompatibility. However, little attention has been paid to high Nb-containing biomedical alloys. Here, the 50 wt.%Nb-XTi-Zr ternary alloy(x = 20wt.%, 30 wt.%, 40 wt.%) with relative density over 90% was prepared by powder metallurgy method. The massive α(Zr) distributed along the grain boundaries and lamellar β(Zr) appeared in the grains of β(Nb) in the 50 wt.%Nb-20wt.%Ti-Zr alloy. The acicular α phase is mainly distributed in the β-grain of 50 wt.%Nb-30wt.%Ti-Zr alloy. And α(Ti)-colonies in the β-grains and continuous α(Ti)GB at β-grain boundary can be observed in the 50 wt.%Nb-40wt.%Ti-Zr alloy. Comparing with Nb-20wt.%Ti-Zr alloy and 50 wt.%Nb-40wt.%Ti-Zr alloy, the 50 wt.%Nb-30wt.%Ti-Zr alloy showed lower Vickers hardness and elastic modulus. Furthermore, the as-sintered 50 wt.%Nb-XTi-Zr alloy promoted the cell proliferation and cell adhesion of MG-63 cells on the surface of alloys. In conclusion, the 50 wt.%Nb-XTi-Zr alloy combines excellent mechanical and biological properties, and the 50 wt.%Nb-30wt.%Ti-Zr alloy with lower elastic modulus (close to the bone) is a more promising candidate for bone implant material.



中文翻译:

用于骨科植入物的 Nb-Ti-Zr 合金

铌(Nb)、钛(Ti)和锆(Zr)以其优异的机械性能和生物相容性作为植入材料备受关注。然而,很少有人关注高含铌的生物医学合金。本文采用粉末冶金法制备了相对密度超过90%的50 wt.% Nb-XTi-Zr三元合金(x = 20wt.%, 30 wt.%, 40 wt.%)。50wt.%Nb-20wt.%Ti-Zr合金的β(Nb)晶粒中出现沿晶界分布的块状α(Zr)和片状β(Zr)。针状α相主要分布在50wt.%Nb-30wt.%Ti-Zr合金的β晶中。β-晶粒中的α(Ti)-集落和连续的α(Ti) GB在 50 wt.%Nb-40wt.%Ti-Zr 合金中可以观察到 β 晶界处。与Nb-20wt.%Ti-Zr合金和50wt.%Nb-40wt.%Ti-Zr合金相比,50wt.%Nb-30wt.%Ti-Zr合金的维氏硬度和弹性模量较低。此外,烧结后的 50 wt.% Nb-XTi-Zr 合金促进了 MG-63 细胞在合金表面的细胞增殖和细胞粘附。综上所述,50 wt.%Nb-XTi-Zr 合金兼具优异的力学和生物学性能,而弹性模量较低(接近骨)的 50 wt.%Nb-30wt.%Ti-Zr 合金更有希望骨植入材料的候选者。

更新日期:2020-11-06
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