Controllable rhodium(III)-catalyzed tandem [3+2] cyclization of aromatic aldehydes with maleimides is developed for the divergent synthesis of stereoselective indane-fused pyrrolidine-2,5-dione. Switchable access to different products could be achieved by employing different additives and varying the reaction time. This atom-economic transformation proceeds efficiently via the C–H bond activation directed by weakly coordinating aldehydes and is characterized by exclusive stereoselectivity, air atmosphere, and being free of nitrogen-based transient directing groups.

中文翻译：

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马来酰亚胺与芳香醛的可控串联[3 + 2]环化反应：铑（III）催化茚满吡咯烷2,5-二酮的发散合成

开发了可控制的铑（III）催化的顺丁烯醛与马来酰亚胺的串联[3 + 2]环化反应，用于发散合成立体选择性的茚满稠合的吡咯烷-2,5-二酮。通过使用不同的添加剂并改变反应时间，可以实现对不同产品的可切换访问。这种原子经济的转变通过弱配位的醛通过C–H键的活化而有效地进行，其特征是具有独特的立体选择性，空气气氛，并且不含氮基的瞬态导向基团。