Introduction: The novel severe-acute-respiratory-syndrome-coronavirus-2 (SARS-CoV-2) virus has led to the ongoing Coronavirus disease 2019 (COVID-19) disease pandemic. There are increasing reports of extrapulmonary clinical features of COVID-19, either as initial presentations or sequelae of disease. We report a patient diagnosed with subacute thyroiditis precipitated by COVID-19 infection, as well as review the literature of similar cases. Case Presentation: A 41-year-old female with no significant personal or family history of endocrinologic disorders presented with clinical features of thyroiditis that began after COVID-19 infection. Clinical, laboratory, and radiologic findings were indicative of subacute thyroiditis. Workup for potential triggers other than SARS-CoV-2 was negative. Discussion/Conclusion: We compared the clinical and diagnostic findings of our patient with other well-documented cases of subacute thyroiditis presumed to be triggered by SARS-CoV-2 viral infection. We also reviewed the literature related to the potential mechanisms leading to thyroiditis. Clinicians must be aware of the possibility of thyroid dysfunction after COVID-19 infection. Early recognition and timely anti-inflammatory therapy help in successful management.
Eur Thyroid J

中文翻译：

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COVID-19 感染引起的亚急性甲状腺炎：病例报告和文献回顾

简介：新型严重急性呼吸综合征冠状病毒 2 (SARS-CoV-2) 病毒导致了持续的 2019 年冠状病毒病 (COVID-19) 疾病大流行。越来越多的关于 COVID-19 肺外临床特征的报道，无论是最初的表现还是疾病的后遗症。我们报告了一名因 COVID-19 感染而被诊断为亚急性甲状腺炎的患者，并回顾了类似病例的文献。病例介绍：一名 41 岁的女性，没有明显的内分泌疾病个人或家族史，在 COVID-19 感染后出现甲状腺炎的临床特征。临床、实验室和放射学检查结果提示亚急性甲状腺炎。对 SARS-CoV-2 以外的潜在触发因素的检查结果为阴性。讨论/结论：我们将我们患者的临床和诊断结果与其他有据可查的推测由 SARS-CoV-2 病毒感染引发的亚急性甲状腺炎病例进行了比较。我们还回顾了与导致甲状腺炎的潜在机制相关的文献。临床医生必须意识到 COVID-19 感染后甲状腺功能障碍的可能性。早期识别和及时的抗炎治疗有助于成功管理。
欧洲甲状腺杂志