Abstract

Antibiotic resistance genes (ARGs) are emerging contaminants, which have been frequently detected in different aquatic environments, posing potential risk to public health and ecosystem. A properly designed and operated wastewater treatment process can be an effective final barrier for reducing the quantity of ARGs discharged into the environment. In order to control the propagation of antimicrobial resistance in the environment, it is essential to comprehensively understand the elimination and inactivation of ARGs by various wastewater treatment processes. This review systematically summarized and analyzed the feasibility and efficiency of ARGs removal in different wastewater treatment processes, including biological processes, such as membrane bioreactor process and constructed wetlands; chemical processes, such as ozonation, chlorination, Fenton oxidation and other advanced oxidation processes (AOPs); physicochemical processes, such as UV radiation, ionizing radiation; and physical processes, such as coagulation and membrane filtration. In addition, the advantages and limitations as well as future direction of these treatment processes for the elimination and inactivation of ARGs in wastewater were also discussed, aiming to provide better understanding and support for future research.

摘要

抗生素抗性基因（ARGs）是一种新兴的污染物，在不同的水生环境中经常被检测到，对公共健康和生态系统构成潜在风险。正确设计和操作的废水处理过程可以成为减少排放到环境中的 ARG 数量的有效最终屏障。为了控制环境中抗菌素耐药性的传播，必须全面了解各种废水处理过程对 ARGs 的消除和灭活。本综述系统总结和分析了不同废水处理工艺中ARGs去除的可行性和效率，包括生物工艺，如膜生物反应器工艺和人工湿地；化学过程，如臭氧化、氯化、芬顿氧化和其他高级氧化工艺（AOP）；物理化学过程，如紫外线辐射、电离辐射；物理过程，如混凝和膜过滤。此外，还讨论了这些处理工艺在废水中去除和灭活 ARGs 的优势和局限性以及未来方向，旨在为未来的研究提供更好的理解和支持。