Even after decades of research, one of the most significant challenges in nanotechnology‐based cancer therapy is to increase the target specificity and to reduce the side effects. As a result, even after substantial progress in lab‐scale research, clinical trials have mostly failed. One of the emerging new strategies to increase the target specificity and to increase the chemotherapeutic efficacy is to mimic biological moieties using cellular membranes. Owing to its preferential accumulation at the tumor site, cancer cell membrane presents itself as a promising surface functionalization to the nanocarriers. This review aims to summarize recent reports on the cancer cell membrane and the hybrid membrane‐associated research for the comprehensive understanding of their successful implementation in cancer therapy.

中文翻译：

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癌细胞膜技术用于癌症治疗

即使经过数十年的研究，基于纳米技术的癌症治疗中最重大的挑战之一是提高靶标特异性并减少副作用。结果，即使在实验室规模的研究取得了实质性进展之后，临床试验大多还是失败了。增加靶标特异性和增加化学治疗功效的新兴策略之一是使用细胞膜模拟生物部分。由于其在肿瘤部位的优先积累，癌细胞膜将其自身展现为纳米载体的有前途的表面功能化。这篇综述旨在总结关于癌细胞膜和混合膜相关研究的最新报道，以全面了解它们在癌症治疗中的成功实施。