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Should WEE(1) CHK(1) in on the FAM(122A)ily?
Molecular Cell ( IF 16.0 ) Pub Date : 2020-11-05 , DOI: 10.1016/j.molcel.2020.10.011
Rebecca Caeser , Triparna Sen

Li et al. (2020) elucidate the resistance mechanisms to small-molecule inhibitors targeting the G2/M cell cycle checkpoint kinase, CHK1, in a variety of non-small cell lung cancer cell lines using CRISPR-mediated genetic approaches and identify biomarkers of response.



中文翻译:

FEE(122A)上应该插入WEE(1)CHK(1)吗?

Li等。(2020)使用CRISPR介导的遗传方法阐明了针对多种非小细胞肺癌细胞系中针对G2 / M细胞周期检查点激酶CHK1的小分子抑制剂的耐药机制,并确定了反应的生物标记。

更新日期:2020-11-06
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