Silver-doped zinc oxide nanoparticles (Ag-ZnO NPs) were successfully synthesized by the Sol-gel method coated with polyethylene glycol as a stabilizing and capping agent. The UV-Vis spectrophotometer analysis was done to analyze the optical property of the nanoparticles. XRD pattern showed the hexagonal structure of ZnO nanoparticles and the reduction in the intensity of the peaks of Ag-ZnO NPs indicates the incorporation of Ag⁺ ions in the ZnO lattices. The surface structural properties of the NPs were confirmed by Field Emission Scanning Electron Microscope (FE-SEM), High Resolution Transmission Electron Microscopy (HRTEM) and Selected Area Electron Diffraction (SAED). The elemental composition of nanoparticles was confirmed by EDAX and XRF-Spectroscopy. The functional group of ZnO and Ag nanoparticles were determined by FT-IR spectroscopy. The photocatalytic activity of Ag-ZnO NPs was studied against ponceau and the maximum degradation percentage was observed to be 89% at 140 min. Further, Ag-ZnO NPs unveiled high potent antibacterial activity against the selected bacterial pathogens and it also rendered significant anticancer activity in UVB-induced HaCaT cells. Consequently, the fluorescent microscopic analysis confirmed the increasing Reactive Oxygen Species (ROS) generation and Mitochondrial Membrane Potential (MMP) loss in the HaCaT cells that leads to the apoptosis induction. Hence, the selected combination of nanoparticles has proven to exhibit higher photocatalytic, antibacterial and anticancer activity. In the near future, it could be an efficient tool for eradicating the dye pollution from wastewater and also preferably be utilized in the cosmetics and pharmaceutical industries to prevent skin cancer.

通过溶胶-凝胶法成功地合成了掺银的氧化锌纳米粒子（Ag-ZnO NPs），并用聚乙二醇作为稳定剂和封端剂。进行紫外可见分光光度计分析以分析纳米颗粒的光学性质。XRD图谱显示了ZnO纳米颗粒的六边形结构，Ag-ZnO NPs峰强度的降低表明Ag ⁺的结合离子在ZnO晶格中。通过场发射扫描电子显微镜（FE-SEM），高分辨率透射电子显微镜（HRTEM）和选定区域电子衍射（SAED）确认了NP的表面结构特性。纳米粒子的元素组成通过EDAX和XRF光谱法确认。ZnO和Ag纳米颗粒的官能团通过FT-IR光谱法测定。研究了Ag-ZnO NPs对丽春红藻的光催化活性，在140 min时最大降解百分数为89％。此外，Ag-ZnO NPs对选定的细菌病原体具有强大的抗菌活性，并且在UVB诱导的HaCaT细胞中也具有显着的抗癌活性。所以，荧光显微镜分析证实，HaCaT细胞中活性氧（ROS）产生的增加和线粒体膜电位（MMP）的损失，导致凋亡的诱导。因此，已证明所选的纳米颗粒组合具有较高的光催化，抗菌和抗癌活性。在不久的将来，它可能是一种消除废水中染料污染的有效工具，并且最好用于化妆品和制药行业，以预防皮肤癌。