Histoplasmosis is a fungal infection caused by Histoplasma capsulatum and very few cases reported from North-West India. Adrenal histoplasmosis is an even more uncommon mycotic disease. We describe five immunocompetent men with adrenal histoplasmosis presenting with constitutional symptoms. Four patients had bilateral adrenal involvement, whereas one had unilateral adrenal mass. Three patients had adrenal insufficiency at presentation and the other two developed adrenal insufficiencies during follow-up. All the patients received amphotericin B and itraconazole treatment which led to symptomatic improvement but adrenal insufficiency persisted in all patients at the end of the follow-up.


中文翻译：

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免疫功能正常个体的肾上腺组织胞浆菌病来自印度西北部拉贾斯坦省的病例系列：新出现的地方病焦点


组织胞浆菌病是一种由荚膜组织胞浆菌引起的真菌感染，印度西北部报告的病例很少。肾上腺组织胞浆菌病是一种更为罕见的真菌性疾病。我们描述了五名具有全身症状的肾上腺组织胞浆菌病的免疫功能正常的男性。4 名患者双侧肾上腺受累，1 名单侧肾上腺肿块。三名患者在就诊时出现肾上腺功能不全，另外两名患者在随访期间出现肾上腺功能不全。所有患者均接受两性霉素 B 和伊曲康唑治疗，症状改善，但随访结束时所有患者仍存在肾上腺功能不全。