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State of recent literature on communication about cancer genetic testing among Latinx populations
Journal of Genetic Counseling ( IF 1.9 ) Pub Date : 2020-11-03 , DOI: 10.1002/jgc4.1351
Daniel Chavez-Yenter 1, 2 , Wen-Ying Sylvia Chou 3 , Kimberly A Kaphingst 1, 2
Affiliation  

Cancer-related genetic testing (hereafter CGT) has transformed cancer prevention, treatment, and care. Researchers debate whether diffusion and use of genetic testing will reduce or widen cancer health disparities through effects on improving or worsening cancer-related mortality, morbidity, and outcomes that disproportionately affect racial and ethnic minority populations. Cancer disparities by race and ethnicity have been associated with social determinants of health and healthcare access and experience. However, little research has explored how communication about CGT may contribute to these disparities. As such, the goal of this study was to characterize the literature published between 2010 and 2017 on communication about CGT among Latinx populations through a secondary analysis of papers identified in a larger scoping review. We found thirteen (2.5%) of 513 papers in the parent scoping review had over 50% Latinx representation; only nine of these (69%) had fully Latinx comprised study cohorts. The majority of the 13 identified studies (n = 9) were conducted to assess knowledge and attitudes regarding CGT. Most studies included services or materials in both Spanish and English. Few studies assessed language preference or acculturation or compared outcomes across sub-ethnicities. We identified opportunities for researchers to explore differences in outcomes by language preference and acculturation, and between sub-ethnicities in future studies. Leveraging a greater understanding of the heterogeneity within the Latinx population will allow genetics researchers and providers to improve utilization of CGT and therein health outcomes to advance health equity.

中文翻译:

关于拉丁裔人群癌症基因检测交流的最新文献状况

癌症相关基因检测(以下简称 CGT)已经改变了癌症的预防、治疗和护理。研究人员争论基因检测的传播和使用是否会通过改善或恶化癌症相关死亡率、发病率和不成比例地影响种族和少数民族人口的结果来减少或扩大癌症健康差异。种族和民族的癌症差异与健康的社会决定因素以及医疗保健的获取和经验有关。然而,很少有研究探讨有关 CGT 的沟通如何导致这些差异。因此,本研究的目的是通过对更大范围审查中确定的论文进行二次分析,来描述 2010 年至 2017 年间发表的关于拉丁裔人群之间 CGT 交流的文献。我们发现,在母版范围审查的 513 篇论文中,有 13 篇(2.5%)的拉丁语代表超过 50%;其中只有九个(69%)具有完全由拉丁裔组成的研究队列。13 项确定的研究中的大多数(n  = 9) 用于评估有关 CGT 的知识和态度。大多数研究包括西班牙语和英语的服务或材料。很少有研究评估语言偏好或文化适应或跨亚种族比较结果。我们确定了研究人员在未来研究中通过语言偏好和文化适应以及亚种族之间探索结果差异的机会。利用对拉丁裔人口异质性的更深入了解,遗传学研究人员和提供者将能够提高 CGT 的利用率以及健康结果,从而促进健康公平。
更新日期:2020-11-03
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