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Bone Tissue Engineering: Attachment of Ultralow Amount of Engineered Plant Viral Nanoparticles to Mesenchymal Stem Cells Enhances Osteogenesis and Mineralization (Adv. Healthcare Mater. 21/2020)
Advanced Healthcare Materials ( IF 10.0 ) Pub Date : 2020-11-04 , DOI: 10.1002/adhm.202070077
Ying‐Ying Lin , Juliane Schuphan , Christina Dickmeis , Eva Miriam Buhl , Ulrich Commandeur , Horst Fischer

In article number 2001245 by Ulrich Commandeur, Horst Fischer, and co‐workers, plant virus nanoparticles, engineered with functional peptides, are laden in mesenchymal stem cellembedded hydrogels at an ultralow concentration for generating a bone substitute. Their competence in stimulation of mineralization and osteogenesis, and the superiority of enriched functional peptides on its surface are verified, demonstrating an excellent candidate for hydrogel composites in bone tissue engineering.
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中文翻译:

骨组织工程:将超低量的工程化植物病毒纳米颗粒附着于间充质干细胞可增强成骨作用和矿化作用(Adv。Healthcare Mater。21/2020)

Ulrich Commandeur,Horst Fischer及其同事在编号为2001245的文章中,将经功能肽修饰的植物病毒纳米颗粒以超低浓度装载于间充质干细胞包埋的水凝胶中,以生成骨替代物。验证了它们在刺激矿化和成骨方面的能力以及其表面富集的功能性肽的优越性,证明了骨组织工程中水凝胶复合材料的极佳候选者。
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更新日期:2020-11-04
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