Background

Isolated subclavian or brachiocephalic artery are uncommon aortic arch anomalies. Here we report the anatomy and histology of this disease.

Methods

Four cases of congenital isolated subclavian or brachiocephalic artery in fetuses are described.

Results

We identified one case of right aortic arch with isolated left subclavian artery associated with the tetralogy of Fallot, two cases of right aortic arch with isolated left brachiocephalic artery (one case with left retro-aortic brachiocephalic vein), and one case of left aortic arch with isolated right subclavian artery associated with coarctation of the aorta and cervical aortic arch. The proximal subclavian or brachiocephalic artery is arterial duct.

Conclusion

Aortic arches with an isolated subclavian or brachiocephalic artery are often associated with the tetralogy of Fallot. It also can be associated with rare abnormalities such as left retro-aortic brachiocephalic vein or cervical aortic arch. Isolated LBA can be associated with microdeletion chromosome 22q11.

中文翻译：

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法洛氏四联症的分离锁骨下或头颅动脉，左后主动脉头颅静脉

背景

孤立的锁骨下或头颅动脉是罕见的主动脉弓异常。在这里，我们报告这种疾病的解剖学和组织学。

方法

描述了四例胎儿先天性锁骨下锁骨下或头颅动脉。

结果

我们确定了1例右主动脉弓与孤立的法洛四联症相关的左锁骨下动脉，2例右主动脉弓与孤立的左臂头脑动脉（1例具有左主动脉后臂头静脉）和1例左主动脉弓右锁骨下右动脉孤立，主动脉和颈主动脉弓缩窄。锁骨下近端或头臂动脉近端是动脉导管。

结论

具有分离的锁骨下动脉或头颅动脉的主动脉弓经常与法洛四联症相关。它也可能与罕见的异常有关，例如左主动脉后臂头静脉或颈主动脉弓。分离的LBA可与微缺失染色体22q11相关。