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Synthesis of Quinoxalin-2(1H)-ones and Hexahydroquinoxalin-2(1H)-ones via Oxidative Amidation–Heterocycloannulation
SynOpen Pub Date : 2020-08-18 , DOI: 10.1055/s-0040-1707203
Krishnaji Tadiparthi 1 , U. K. Syam Kumar 2 , Akula Raghunadh 2 , Suresh Babu Meruva 2 , V. Narayana Murthy 2 , L. Vaikunta Rao 3
Affiliation  

A metal-catalyst-free synthesis of substituted quinoxalin-2-ones from 2,2-dibromo-1-arylethanone by employing an oxidative amidation–heterocycloannulation protocol is reported. The substrate scope of the reaction has been demonstrated and a possible mechanism for this reaction has also been proposed.



中文翻译:

氧化酰胺化-杂环环化法合成喹喔啉-2(1H)-one和六氢喹喔啉-2(1H)-one

据报道,采用氧化酰胺化-杂环环化方法可从2,2-二溴-1-芳酮中无金属催化剂合成取代的喹喔啉-2-酮。已经证明了反应的底物范围,并且还提出了该反应的可能机理。

更新日期:2020-08-18
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