A large F2 cross with 920 Japanese quail was used to map QTL for phosphorus utilization, calcium utilization, feed per gain and body weight gain. In addition, four bone ash traits were included, because it is known that they are genetically correlated with the focal trait of phosphorus utilization. Trait recording was done at the juvenile stage of the birds. The individuals were genotyped genome‐wide for about 4k SNPs and a linkage map constructed, which agreed well with the reference genome. QTL linkage mapping was performed using multimarker regression analysis in a line cross model. Single marker association mapping was done within the mapped QTL regions. The results revealed several genome‐wide significant QTL. For the focal trait phosphorus utilization, a QTL on chromosome CJA3 could be detected by linkage mapping, which was substantiated by the results of the SNP association mapping. Four candidate genes were identified for this QTL, which should be investigated in future functional studies. Some overlap of QTL regions for different traits was detected, which is in agreement with the corresponding genetic correlations. It seems that all traits investigated are polygenic in nature with some significant QTL and probably many other small‐effect QTL that were not detectable in this study.

中文翻译：

---

在日本鹌鹑中使用4k SNP连锁图谱定位磷利用及相关性状的基因

使用一个大型F2杂交种和920只日本鹌鹑来绘制QTL的磷利用，钙利用，单位增重饲料和体重增加量。另外，还包括四个骨灰性状，因为已知它们与磷利用的主要性状在遗传上相关。在幼鸟阶段进行性状记录。对个体进行全基因组基因分型，得到约4k个SNP，并构建了一个连锁图谱，该图谱与参考基因组非常吻合。在线交叉模型中使用多标记回归分析进行QTL连锁作图。在标记的QTL区域内完成了单个标记关联的映射。结果显示了几个全基因组重要的QTL。对于焦点性状的磷利用，可通过连锁作图检测出CJA3染色体上的QTL，这由SNP关联映射的结果证实。已为该QTL鉴定了四个候选基因，应在以后的功能研究中对其进行研究。检测到不同性状的QTL区域有一些重叠，这与相应的遗传相关性一致。似乎所有被研究的性状在本质上都是多基因的，具有一些重要的QTL，可能还有许多其他在本研究中无法检测到的小效应QTL。