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A Selective Sweep Conceals a MicroRNA with Broad Metabolic Effects
Cell Metabolism ( IF 29.0 ) Pub Date : 2020-11-03 , DOI: 10.1016/j.cmet.2020.10.014
Iain Mathieson , Struan F.A. Grant

The need for discovering new genes driving metabolic disease susceptibility is clear; even clearer is the need for their subsequent functional characterization. A new paper reports a role for miR-128-1 in metabolic control through a series of elegant mouse studies, and an intriguing hypothesis about its “thrifty” role in metabolism.



中文翻译:

选择性扫描隐藏了具有广泛代谢作用的MicroRNA。

很显然,发现驱动代谢疾病易感性的新基因的需求;更明确的是它们随后的功能表征需求。一篇新论文通过一系列精美的小鼠研究报告了miR-128-1在代谢控制中的作用,以及有关其“节俭”在代谢中作用的有趣假设。

更新日期:2020-11-03
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