The density, sound velocity and viscosity of doxycycline hyclate in water, aqueous solution of L-phenylalanine and aqueous solution of glycyl glycine have been determined at different temperatures (305.15, 310.15, 315.15 and 320.15) K. The calculated values of partial molar volume (V), standard partial molar volume of transfer (Δ_tr,V), partial molar adiabatic compressibility (κ,_s) and partial molar adiabatic compressibility of transfer (Δ_tr, κ,_s) for doxycycline hyclate in water, aqueous solution of L-phenylalanine and aqueous solution of glycyl glycine infer the dominance of ion-hydrophilic interactions over hydrophobic-hydrophobic interactions. The Jones-Dole viscosity B-coefficient, viscosity B-coefficient of transfer (ΔtrB), free energy of activation of viscous flow per mole of pure solvent (Δµ) and solute (Δµ^*) respectively, activation entropy (Δs^*) and activation enthalpy (ΔH^*) of doxycycline hyclate in water, aqueous solution of L-phenylalanine and aqueous solution of glycyl glycine also have been calculated using viscosity data. The structure making and breaking behaviour of doxycycline hyclate in water, aqueous solution of L-phenylalanine and aqueous solution of glycyl glycine are obtained from the values of Hepler’s constant i.e. (δ²V/δT²) and (dB/dT). The presence and absence of caging effect has been studied with the help of partial molar adiabatic expansibility (E). The isobaric thermal expansion coefficient (α^o = E/V), intermolecular free length and acoustic impedance for doxycycline hyclate in water, aqueous solution of L-phenylalanine and aqueous solution of glycyl glycine also have been determined.

中文翻译：

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通过使用体积，超声和粘度参数研究在不同温度下水，L-苯丙氨酸水溶液和甘氨酰甘氨酸中盐酸多西环素的分子相互作用

在不同温度（305.15、310.15、315.15和320.15）K下测定了盐酸多西环素在水中，L-苯丙氨酸的水溶液和甘氨酰甘氨酸的水溶液中的密度，声速和粘度。 V ），标准的部分摩尔绝热体积（_Δtr，V ），部分的摩尔绝热可压缩性（κ ，_s）和部分摩尔的绝热压缩性（_Δtr，κ ，_s）对于多西环素在水中的盐酸盐，L-苯丙氨酸的水溶液和甘氨酰甘氨酸的水溶液推断离子-亲水相互作用优于疏水-疏水相互作用。琼斯-多尔粘度B系数，转移粘度B系数（ΔtrB），每摩尔纯溶剂（Δµ ）和溶质（Δµ ^*）的粘性流活化的自由能，活化熵（Δs ^*）和活化焓（ΔH ^*）的盐酸多西环素），L-苯丙氨酸水溶液和甘氨酰甘氨酸水溶液也已使用粘度数据进行了计算。结构制造并在水中盐酸强力霉素的断裂行为，L-苯丙氨酸和甘氨酰甘氨酸的水溶液的水溶液从赫普勒常数即（δ的值而获得的² V /δT ²）和（分贝/ DT）。借助部分摩尔绝热可膨胀性（E ）研究了笼统效应的存在与否。等压热膨胀系数（^αo = E / V），还确定了盐酸多西环素在水中，L-苯丙氨酸的水溶液和甘氨酰甘氨酸的水溶液的分子间自由长度和声阻抗。