The consumption of the offal of noncastrated pigs can lead to the excretion of 19‐norandrosterone (NorA) in urine of humans. In doping control, GC/C/IRMS is the method of choice to differentiate between an endogenous or exogenous origin of urinary NorA. In some cases, after the consumption of wild boar offal, the δ¹³C values of urinary NorA fulfill the criteria of an adverse analytical finding due to differing food sources of boar and consumer. However, consumption of wild boar's offal is not very common in Germany, and thus, the occurrence of such an analytical finding is unlikely. In contrast, the commerce with wild boar meat has increased in Germany within the last years. Up to 20,000 tons of wild boar meat are annually consumed. In order to probe for the probability of the occurrence of urinary NorA after consumption of wild boar meat, human urine samples were tested following the ingestion of commercially available game. In approximately half of the urine samples, traces of NorA were detected postadministration of 200 to 400 g boar meat. The highest urinary concentration was 2.9 ng/ml, and significant amounts were detected up to 9 h after the meal. δ¹³C values ranged from −18.5‰ to −23.5‰, which would have led to at least two adverse analytical findings if the samples were collected in an antidoping context. IRMS analysis on German boar tissue samples showed that δ¹³C values for wild boar's steroids are unpredictable and may vary seasonally.

中文翻译：

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食用野猪肉后 19-去甲雄酮的排泄

食用未阉割的猪的内脏会导致人类尿液中 19-去甲雄酮 (NorA) 的排泄。在兴奋剂控制中，GC/C/IRMS 是区分尿液 NorA 的内源性或外源性来源的首选方法。在某些情况下，食用野猪内脏后，δ ¹³由于公猪和消费者的食物来源不同，尿液 NorA 的 C 值符合不良分析结果的标准。然而，食用野猪内脏在德国并不常见，因此不太可能出现这样的分析结果。相比之下，德国的野猪肉贸易在过去几年有所增加。每年消耗多达 20,000 吨的野猪肉。为了探讨食用野猪肉后尿中NorA发生的可能性，在摄入市售野味后对人体尿液样本进行了检测。在大约一半的尿液样本中，在服用 200 至 400 克野猪肉后检测到痕量 NorA。最高尿浓度为 2.9 ng/ml，并且在餐后 9 小时内检测到显着浓度。δ¹³ C 值范围从 -18.5‰ 到 -23.5‰，如果在反兴奋剂环境中收集样品，这将导致至少两个不利的分析结果。对德国公猪组织样本的 IRMS 分析表明，野猪类固醇的δ ¹³ C 值是不可预测的，并且可能随季节变化。