当前位置: X-MOL 学术Trends Biotechnol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Arming Yourself for The In Silico Protein Design Revolution
Trends in Biotechnology ( IF 17.3 ) Pub Date : 2020-10-31 , DOI: 10.1016/j.tibtech.2020.10.003
Sidney P Walker 1 , Venkata V B Yallapragada 1 , Mark Tangney 2
Affiliation  

Proteins mediate many essential processes of life to a degree of functional precision unmatched by any synthetic device. While engineered proteins are currently used in biotech, food, biomedicine, and material technology-based industries, the true potential of proteins is practically untapped. The emerging field of in silico protein design is predicted to provide the next quantum leap in the biotech industry. Having predictive control over protein function and the ability to redefine these functions have driven the field of protein engineering into an era of unprecedented development. This article provides a holistic analysis of protein design R&D (current state-of-the-art tools and knowhow) and commercial landscape, as well as a one-stop-shop profile of in silico protein design technology for biotechnology stakeholders.



中文翻译:

为硅胶蛋白质设计革命武装自己

蛋白质介导生命的许多基本过程,其功能精确度是任何合成装置都无法比拟的。虽然工程蛋白质目前用于生物技术、食品、生物医学和基于材料技术的行业,但蛋白质的真正潜力实际上尚未开发。计算机蛋白质设计的新兴领域预计将为生物技术行业提供下一个巨大的飞跃。对蛋白质功能的预测控制以及重新定义这些功能的能力将蛋白质工程领域推向了前所未有的发展时代。本文提供了对蛋白质设计研发(当前最先进的工具和技术)和商业前景的整体分析,以及在 silico 生物技术利益相关者的蛋白质设计技术。

更新日期:2020-10-31
down
wechat
bug