Alternative splicing is a common but complex posttranscriptional regulatory process in eukaryotes, through which multiple different transcripts are produced from a single pre-mRNA. An increasing number of studies have revealed that alternative splicing is widespread in fungi. Intron retention (IR) is considered the most prevalent splicing type due to the relatively short introns and long exons involved in this process. Alternative splicing is coordinated by a variety of factors, including genomic structure characteristics, TPP riboswitches, splicing factors and DNA methylation, and is involved in the regulation of growth and development, and the improvement of survivability and pathogenicity. Taken together, the results show that alternative splicing events are fungal evolutionary adaptations to changing external conditions.

选择性剪接是真核生物中常见但复杂的转录后调控过程，通过该过程可从单个pre-mRNA产生多个不同的转录本。越来越多的研究表明，选择性剪接在真菌中很普遍。内含子保留（IR）被认为是最普遍的剪接类型，因为该过程涉及相对较短的内含子和较长的外显子。可变剪接受多种因素的协调，包括基因组结构特征，TPP核糖开关，剪接因子和DNA甲基化，并参与生长和发育的调节以及生存能力和致病性的提高。两者合计，结果表明替代剪接事件是真菌进化适应外部条件的变化。