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A New Flavonoid Glycoside from Scutellaria barbata
Chemistry of Natural Compounds ( IF 0.8 ) Pub Date : 2020-10-31 , DOI: 10.1007/s10600-020-03217-6
Yang Liu , Xu-Hua Huang , Jia Chen , Jian-Hua Shao , Chun-Chao Zhao

A new flavonoid glycoside 1, together with nine known compounds, has been isolated from Scutellaria barbata D. Don. The structure of compound 1 was elucidated as acacetin 7-O-β-D-galactopyranosyl(1→2)-β-Dglucopyranoside by spectroscopic data (1D and 2D NMR methods) and chemical evidences. Additionally, compound 1 displayed potent inhibitory activity against α-glucosidase with an IC50 value of 8.9 μM in vitro.

中文翻译:

黄芩中一种新的黄酮苷

从 Scutellaria barbata D. Don 中分离出一种新的黄酮苷 1 以及九种已知化合物。通过光谱数据(一维和二维核磁共振方法)和化学证据,化合物 1 的结构被阐明为金合欢苷 7-O-β-D-吡喃半乳糖基(1→2)-β-D-吡喃葡萄糖苷。此外,化合物 1 显示出对 α-葡萄糖苷酶的有效抑制活性,体外 IC50 值为 8.9 μM。
更新日期:2020-10-31
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