Fermentable sugars are a group of pivotal intermediates and platform compounds achieved by the conversion of lignocellulose. Fast pyrolysis, as a little-explored way to liberate levoglucosan from biomass, may have a potential capability to overcome the technical barriers and fundamental limitations for efficient saccharification. Pretreatment prior to fast pyrolysis is essential to improve levoglucosan yield from lignocellulose. Contrary to typical high-temperature acid pretreatments, a pretreatment under mild conditions was evaluated and optimized, where different acid (formic acid, acetic acid, oxalic acid, nitric acid, phosphoric acid, sulphuric acid and hydrochloric acid) were employed at room temperature prior to fast pyrolysis of lignocellulose. Due to the alteration of chemical compositions and physical structures of biomass, especially the elimination of alkali and alkaline earth metals, the levoglucosan yield of dilute acid pretreated biomass was improved remarkably as compared with that of raw material, meanwhile claimed that acid pretreatments at room temperature had an enough capability in efficient utilization of biomass. In sum, this study offered a novel and economical strategy for selective saccharification of lignocellulose for industrialized bio-refinery.

可发酵糖是通过木质纤维素的转化获得的一组关键中间体和平台化合物。快速热解作为从生物质中释放左旋葡聚糖的一种鲜为人知的方法，可能具有克服技术障碍和有效糖化的基本限制的潜在能力。快速热解之前的预处理对于提高木质纤维素的左旋葡聚糖产量至关重要。与典型的高温酸预处理相反，对温和条件下的预处理进行了评估和优化，其中先于室温使用不同的酸（甲酸，乙酸，草酸，硝酸，磷酸，硫酸和盐酸）。可以快速热解木质纤维素。由于生物质的化学成分和物理结构发生变化，特别是消除了碱金属和碱土金属，稀酸预处理生物质的左旋葡聚糖产率比原料明显提高，同时声称在室温下酸预处理具有足够的生物质有效利用能力。总而言之，这项研究为木质纤维素的选择性糖化工业化生物精炼提供了一种新颖而经济的策略。