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Upregulation of C-Reactive Protein by Placenta-Derived Mesenchymal Stem Cells Promotes Angiogenesis in A Rat Model with Cirrhotic Liver.
International Journal of Stem Cells ( IF 2.3 ) Pub Date : 2020-10-31 , DOI: 10.15283/ijsc20052
Ji Hye Jun 1 , Jieun Jung 2 , Jae Yeon Kim 1 , Seong-Gyu Hwang 3 , Si Hyun Bae 4 , Gi Jin Kim 1
Affiliation  

Liver cirrhosis is accompanied by abnormal vascular shunts. The Wnt pathway is essential for endothelial cell survival and proliferation. C-reactive protein (CRP), which is produced by hepatocyte, activates angiogenesis in cardiovascular diseases.

中文翻译:

胎盘来源的间充质干细胞上调 C 反应蛋白促进肝硬化大鼠模型的血管生成。

肝硬化伴有异常的血管分流。Wnt 通路对内皮细胞的存活和增殖至关重要。由肝细胞产生的 C 反应蛋白 (CRP) 可激活心血管疾病中的血管生成。
更新日期:2020-11-03
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