Background: Severe burn injury results in substantial damage to the skin, inhibiting its ability to perform as the primary barrier to infection. Additionally, severe burn injury can lead to critical illness and extensive time in the intensive care unit (ICU). These two factors work to increase the risk of sepsis in the burn patient compared with other hospitalized patients. The increased risk of sepsis is compounded by the difficulty of diagnosing sepsis in severely burned patients because the pathophysiology of large burns mimics sepsis, leading to possible delay in diagnosis and initiation of treatment.

中文翻译：

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2020年烧伤患者脓毒症回顾

背景：严重烧伤会对皮肤造成严重损害，抑制其作为感染主要屏障的能力。此外，严重的烧伤可能导致重症监护病房 (ICU) 中的危重疾病和长时间。与其他住院患者相比，这两个因素会增加烧伤患者发生败血症的风险。由于大面积烧伤的病理生理学类似于败血症，因此在严重烧伤患者中诊断败血症的难度增加了败血症风险的增加，从而导致诊断和治疗开始的可能延误。