Using phenolic acids as an example, we continue to study the nature of the previously obtained multilayer sorbents for HPLC—silica gels modified up to two times with 6,10-ionene and dextran sulfate (DS). The chromatographic behavior of this class of compounds on the obtained sorbents was studied. A six-component mixture of sorbic, vanillic, sinapic, - coumaric, caffeic, and ferulic acids was separated on the silica gel twice modified with 6,10-ionene and dextran sulfate in 15 min with a selectivity of up to 1.88 and a column efficiency of up to 26000 theoretical plates per meter. The possibility of separating the two classes of compounds—phenolic acids and basic nitrogen-containing pharmaceuticals—in a single mixture on silica gel, twice modified with 6,10-ionene and dextran sulfate, is shown.

中文翻译：

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在 6,10-紫罗烯和硫酸葡聚糖改性硅胶上进行酚酸的 HPLC 分离

以酚酸为例，我们继续研究先前获得的用于 HPLC 的多层吸附剂的性质 - 用 6,10-紫罗烯和硫酸葡聚糖 (DS) 改性最多两次的硅胶。研究了这类化合物在所得吸附剂上的色谱行为。山梨酸、香草酸、芥子酸、香豆酸、咖啡酸和阿魏酸的六组分混合物在用 6,10-紫罗烯和硫酸葡聚糖改性两次的硅胶上在 15 分钟内分离，选择性高达 1.88 和色谱柱效率高达每米 26000 个理论板。显示了在硅胶上的单一混合物中分离两类化合物——酚酸和碱性含氮药物的可能性，用 6,10-紫罗烯和硫酸葡聚糖改性两次。