Background. The C-reactive protein (CRP)/albumin ratio is a useful index used to represent patient inflammation and nutritional status. Elderly patients are at the highest risk for acute kidney injury (AKI). We clarified the impact of the preoperative CRP/albumin ratio on AKI and evaluated the impact of postoperative AKI on end-stage renal disease (ESRD) among elderly cystectomy patients. Methods. We included elderly of age who underwent radical cystectomy. Multivariate logistic regression analysis and receiver operating characteristic curve analysis were performed to identify risk factors for AKI. Propensity score-matched analysis and conditional logistic regression analysis were performed to elucidate the impact of the CRP/albumin ratio on AKI. The incidence of ESRD was compared between the non-AKI and AKI groups at 12 months after radical cystectomy. Results. AKI occurred in 110 patients (32.2%). The CRP/albumin ratio and 6% hydroxyethyl starch amount were risk factors for postoperative AKI. The optimal cut-off value for the CRP/albumin ratio predicting AKI was 0.1. After propensity score matching, the AKI incidence in the CRP/albumin group was higher than that in the CRP/albumin group (46.7% vs. 20.6%, ), and a CRP/albumin was associated with a higher AKI incidence (, ). The ESRD incidence was higher in the AKI group than in the non-AKI group (7.3% vs. 1.2%, ). Conclusion. A CRP/albumin was associated with an increased incidence of AKI, which was associated with higher ESRD incidence among elderly cystectomy patients.

中文翻译：

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老年患者根治性膀胱切除术后 C 反应蛋白/白蛋白比与急性肾损伤：倾向评分匹配分析

背景。C 反应蛋白 (CRP)/白蛋白比率是用于表示患者炎症和营养状况的有用指标。老年患者发生急性肾损伤 (AKI) 的风险最高。我们阐明了术前 CRP/白蛋白比值对 AKI 的影响，并评估了术后 AKI 对老年膀胱切除术患者终末期肾病 (ESRD) 的影响。方法。我们包括老年人接受根治性膀胱切除术的年龄。进行多变量逻辑回归分析和受试者工作特征曲线分析以确定 AKI 的危险因素。进行倾向评分匹配分析和条件逻辑回归分析以阐明 CRP/白蛋白比率对 AKI 的影响。在根治性膀胱切除术后 12 个月，比较了非 AKI 组和 AKI 组的 ESRD 发生率。结果。110 名患者 (32.2%) 发生 AKI。CRP/白蛋白比和6%羟乙基淀粉量是术后AKI的危险因素。CRP/白蛋白比率预测 AKI 的最佳截止值为 0.1。倾向评分匹配后，CRP/白蛋白中的 AKI 发生率组高于 CRP/白蛋白组（46.7% 对 20.6%，)和 CRP/白蛋白与较高的 AKI 发病率相关（, ）。AKI 组的 ESRD 发生率高于非 AKI 组（7.3% vs. 1.2%，）。 结论。CRP/白蛋白与 AKI 的发生率增加有关，这与老年膀胱切除术患者中更高的 ESRD 发生率有关。