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Analog implementation of a Hodgkin–Huxley model neuron
American Journal of Physics ( IF 0.9 ) Pub Date : 2020-11-01 , DOI: 10.1119/10.0001072
George H. Rutherford 1 , Zach D. Mobille 1 , Jordan Brandt-Trainer 1 , Rosangela Follmann 2 , Epaminondas Rosa 3
Affiliation  

We construct an electronic circuit for mimicking a single neuron's behavior in connection with the dynamics of the Hodgkin–Huxley mathematical model. Our results show that the electronic neuron, even though it contains binary-state circuitry components, displays a timing interplay between the ion channels, which is consistent with the corresponding timing encountered in the model equations. This is at the core of the mechanism determining not only the creation of action potentials but also the neuronal firing rate output. This work is suitable for educational purposes in physics, mathematical modeling, electronics, and neurophysiology and can be extended for implementation in networked neurons for more advanced studies of neuronal behaviors.

中文翻译:

霍奇金-赫胥黎模型神经元的模拟实现

我们构建了一个电子电路,用于模拟与霍奇金-赫胥黎数学模型动力学相关的单个神经元的行为。我们的结果表明,电子神经元即使包含二元状态电路组件,也会显示离子通道之间的时序相互作用,这与模型方程中遇到的相应时序一致。这是不仅决定动作电位的产生而且决定神经元放电率输出的机制的核心。这项工作适用于物理学、数学建模、电子学和神经生理学方面的教育目的,并且可以扩展到网络神经元中的实施,以对神经元行为进行更高级的研究。
更新日期:2020-11-01
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