Objective:To evaluate an abbreviated NIH Toolbox Cognition Battery (NIHTB-CB) protocol that can be administered remotely without any in-person assessments, and explore the agreement between prorated scores from the abbreviated protocol and standard scores from the full protocol.Methods:Participant-level age-corrected NIHTB-CB data were extracted from six studies in individuals with a history of stroke, mild traumatic brain injury (mTBI), treatment-resistant psychosis, and healthy controls, with testing administered under standard conditions. Prorated fluid and total cognition scores were estimated using regression equations that excluded the three fluid cognition NIHTB-CB instruments which cannot be administered remotely. Paired t tests and intraclass correlations (ICCs) were used to compare the standard and prorated scores.Results:Data were available for 245 participants. For fluid cognition, overall prorated scores were higher than standard scores (mean difference = +4.5, SD = 14.3; p < 0.001; ICC = 0.86). For total cognition, overall prorated scores were higher than standard scores (mean difference = +2.7, SD = 8.3; p < 0.001; ICC = 0.88). These differences were significant in the stroke and mTBI groups, but not in the healthy control or psychosis groups.Conclusions:Prorated scores from an abbreviated NIHTB-CB protocol are not a valid replacement for the scores from the standard protocol. Alternative approaches to administering the full protocol, or corrections to scoring of the abbreviated protocol, require further study and validation.

中文翻译：

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美国国立卫生研究院工具箱认知电池简写方案的按比例评分评估

目的：评估一个无需任何亲自评估即可远程管理的简化 NIH Toolbox Cognition Battery (NIHTB-CB) 协议，并探讨简化协议的按比例分配的分数与完整协议的标准分数之间的一致性。方法：参与者年龄校正的 NIHTB-CB 数据是从有中风史、轻度创伤性脑损伤 (mTBI)、难治性精神病和健康对照者的六项研究中提取的，并在标准条件下进行测试。使用排除不能远程管理的三种流体认知 NIHTB-CB 仪器的回归方程估计按比例分配的流体和总认知分数。配对吨测试和组内相关性 (ICCs) 用于比较标准和按比例分配的分数。结果：数据可用于 245 名参与者。对于流体认知，按比例分配的总体分数高于标准分数（平均差 = +4.5，标清= 14.3;p< 0.001; ICC = 0.86)。对于总认知，按比例分配的总体分数高于标准分数（平均差 = +2.7，标清= 8.3;p< 0.001; ICC = 0.88）。这些差异在中风组和 mTBI 组中显着，但在健康对照组或精神病组中不显着。结论：来自缩写 NIHTB-CB 协议的按比例分数不能有效替代标准协议的分数。管理完整方案的替代方法，或对简化方案评分的更正，需要进一步研究和验证。