Introduction: 

Screening for developmental delays during critical periods of infant development is essential for early detection and intervention. Among high-risk infants in resource-limited settings, including those who are HIV exposed, there is a greater need for screening. This study expanded on previous analyses of the Bayley Infant Neurodevelopmental Screener (BINS) by providing psychometric properties to evaluate the appropriateness of using the BINS in a sample of HIV-exposed infants in rural South Africa.

Method: 

A total of 160 mothers with HIV, their infants, and their male partners were recruited. The BINS was administered to the infants, and their weights were recorded. Mothers completed measures of depression, intimate partner violence, male involvement, and adherence. Male partners reported their own involvement in perinatal care.

Results: 

Results demonstrated support for a 5-factor structure consistent with previous transcultural adaptations of the BINS, demonstrating construct validity, and adequate reliability. Convergent validity was partially supported, as shown by associations with intimate partner violence and male involvement as reported by men and women and maternal adherence, although not with birth weight or maternal depression. The BINS showed adequate discriminating power, with only a few low-performing items.

Conclusion: 

In rural South Africa, a resource-limited setting, the BINS seems to be an adequate screening tool for developmental delays in children that may be used to identify those in need of intervention. Considering the high prevalence of delays identified in this study, antiretroviral therapy–exposed and HIV-exposed infants may benefit from further assessment to determine a need for intervention in community-based clinics.

中文翻译：

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南非农村地区艾滋病毒暴露婴儿中的贝利婴儿神经发育筛查仪的验证

介绍： 

对婴儿发育关键时期的发育迟缓进行筛查对于早期发现和干预至关重要。在资源有限的环境中的高危婴儿中，包括那些受到HIV感染的婴儿，对筛查的需求更大。这项研究通过提供心理测量特性来评估在南非农村暴露于HIV的婴儿样本中使用BINS的适当性，从而扩展了先前对Bayley婴儿神经发育筛查（BINS）的分析。

方法： 

总共招募了160名艾滋病毒母亲，婴儿和男性伴侣。对婴儿施用BINS，并记录其体重。母亲完成了抑郁症，亲密伴侣暴力，男性参与和依从性的措施。男性伴侣报告自己参与围产期护理。

结果： 

结果证明了与以前的BINS跨文化改编相一致的5因子结构的支持，证明了结构的有效性和足够的可靠性。聚合效度得到了部分支持，这与男女之间的亲密伴侣暴力和男性参与以及母亲的依从性相关，这与出生体重或孕产妇的抑郁无关，但并非如此。BINS表现出足够的辨别力，只有少量的不良品。

结论： 

在资源匮乏的南非农村地区，BINS似乎是针对儿童发育迟缓的适当筛查工具，可用于确定需要干预的儿童。考虑到本研究中发现的延误患病率很高，因此接受抗逆转录病毒治疗的婴儿和感染HIV的婴儿可能会从进一步的评估中受益，以确定需要对社区诊所进行干预。