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Surface engineered bimetallic nanoparticles based therapeutic and imaging platform: recent advancements and future perspective
Materials Science and Technology ( IF 1.8 ) Pub Date : 2020-10-23 , DOI: 10.1080/02670836.2020.1832323
Rohini Kotha 1 , Gasper Fernandes 1 , Ajinkya Nitin Nikam 1 , Sanjay Kulkarni 1 , Abhijeet Pandey 1 , Sureshwar Pandey 2 , Srinivas Mutalik 1
Affiliation  

The unique physical and chemical properties of monometallic nanoparticles have been comprehensively explored. Analogously, the combination of two metals induces alterations in the system’s electron density, termed as Bimetallic nanoparticles (BMNP’s) were found to be more desirable than monometallic nanoparticles due to improved stability, activity, and selectivity, thus altering the chemical, optical, and electrical properties. In this review, we showcase the importance in the context of biomedical applications. The article sheds light on utilising BMNP’s in the field of theranostics, diagnosis, and therapeutics by focusing on anticancer, antimicrobial and wound healing activity along with the toxicological problems associated with BMNP’s. In conclusion, BMNP’s can be used as a novel therapeutic and diagnostic system to tackle major health concerns. GRAPHICAL ABSTRACT

中文翻译:

基于表面工程双金属纳米粒子的治疗和成像平台:最新进展和未来展望

已经全面探索了单金属纳米粒子独特的物理和化学性质。类似地,由于稳定​​性、活性和选择性的提高,两种金属的组合会引起系统电子密度的改变,被称为双金属纳米粒子 (BMNP) 被发现比单金属纳米粒子更理想,从而改变了化学、光学和电学特性。在这篇评论中,我们展示了生物医学应用背景下的重要性。这篇文章通过关注抗癌、抗菌和伤口愈合活性以及与 BMNP 相关的毒理学问题,阐明了 BMNP 在治疗诊断学、诊断和治疗领域的应用。综上所述,BMNP's 可以用作一种新型的治疗和诊断系统来解决主要的健康问题。图形概要
更新日期:2020-10-23
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