ABSTRACT

Background: Short-Form Six-Dimension version 2 (SF-6Dv2) is a multi-attribute utility instrument that can be used in combination with the SF-36v2 (SF-6Dv2_SF-36) or as an independent instrument in two forms: six questions (SF-6Dv2_ind-6) and 10 questions (SF-6Dv2_ind-10). The purpose of this research was to assess the consistency between the results of the SF-6Dv2_ind-6 and the SF-6Dv2_SF-36 in patients with breast cancer.

Research design and methods: This cross-sectional study was carried out on 418 patients with breast cancer. The degree of agreement between the descriptive systems of instruments was calculated using Spearman’s correlation coefficient, global consistency index (GCI), and identically classified index (ICI).

Results: The average size of the Spearman’s correlation coefficients between the descriptive systems of instruments was higher than 0.5. The results of the GCI revealed that the level of agreement between dimensions of the two instruments had a mean of 64.9 (range 32.45–86.8). The SF-6Dv2_SF-36 generates statistically higher values than does the SF-6Dv2_ind-6, and mean difference between the two instruments was 0.087 for model 3 and 0.027 for model 10.

Conclusions: This study provided evidence that the SF-6Dv2_SF-36 and the SF-6Dv2_ind-6 may produce different answers from patients with breast cancer and lead to a small difference in utility values.

摘要

背景：短型六维第2版（SF-6Dv2）是一种多属性实用仪器，可与SF-36v2（SF-6Dv2 _SF-36）组合使用或作为两种形式的独立仪器使用：六个问题（SF-6Dv2 _ind-6）和10个问题（SF-6Dv2 _ind-10）。本研究的目的是评估 SF-6Dv2 _ind-6和 SF-6Dv2 _SF-36在乳腺癌患者中的结果之间的一致性。

研究设计和方法：这项横断面研究对 418 名乳腺癌患者进行。使用Spearman相关系数、全球一致性指数（GCI）和相同分类指数（ICI）计算工具描述系统之间的一致程度。

结果：仪器描述系统间Spearman相关系数的平均大小均大于0.5。GCI 的结果显示，两种工具的维度之间的一致性水平平均值为 64.9（范围 32.45-86.8）。SF-6Dv2 _SF-36产生的统计值高于 SF-6Dv2 _ind-6，两种仪器之间的平均差异对于模型 3 为 0.087，对于模型 10 为 0.027。

结论：本研究提供的证据表明，SF-6Dv2 _SF-36和 SF-6Dv2 _ind-6可能会产生与乳腺癌患者不同的答案，并导致效用值的微小差异。