An Improved Process for Synthesis of (S)-Duloxetine Hydrochloride Involving Enzymatic Asymmetric Carbonyl Reduction on a Novel Ketoamine,Organic Preparations and Procedures International

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An Improved Process for Synthesis of (S)-Duloxetine Hydrochloride Involving Enzymatic Asymmetric Carbonyl Reduction on a Novel Ketoamine
Organic Preparations and Procedures International ( IF 1.5 ) Pub Date : 2020-10-27 , DOI: 10.1080/00304948.2020.1818527
Sachin A. Sasane ₁ , Mofazzal Husain ₁ , Nandu B. Bhise ₁ , Girij P. Singh ₁ , Alex Joseph ₂ , Gautham G. Shenoy ₂

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(S)-Duloxetine hydrochloride 1 is a medication used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia and neuropathic pain (Figure 1). 1 , 2 Due to its versatility in d...

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