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Vinylbenziodoxol(on)es: Synthetic Methods and Applications
Helvetica Chimica Acta ( IF 1.8 ) Pub Date : 2020-10-30 , DOI: 10.1002/hlca.202000191
Nina Declas 1 , Guillaume Pisella 1 , Jerome Waser 1
Affiliation  

Cyclic hypervalent iodine reagents are now frequently used in synthetic organic chemistry, either as oxidants or group‐transfer reagents. Vinylbenziodoxol(on)es (VBXs) bearing alkene substituents have been less investigated than the corresponding trifluoromethyl or alkynyl reagents. Nevertheless, since 2016 the development of new synthetic methods to access VBXs has awakened the interest of the synthetic community, leading to new transformations highlighting their unique reactivity as electrophilic alkene synthons. In this review, an overview of the synthesis and applications of VBX reagents will be presented. The review is organized according to the two main classes of VBX reagents reported so far – simple alkyl/aryl‐substituted VBXs and heteroatom (S, O, N, X)‐substituted VBXs – as they differ significantly from the point of view of synthetic access.

中文翻译:

乙烯基苯并恶唑醇:合成方法与应用

环状高价碘试剂现在在合成有机化学中经常用作氧化剂或基团转移试剂。与相应的三氟甲基或炔基试剂相比,带有烯基取代基的乙烯基苯并恶唑醇(VBXs)的研究较少。然而,自2016年以来,开发用于访问VBX的新合成方法引起了合成社区的兴趣,导致进行了新的变革,突显了它们作为亲电烯烃合成子的独特反应性。在这篇综述中,将概述VBX试剂的合成和应用。审查是根据迄今为止报道的两大类VBX试剂进行组织的-简单的烷基/芳基取代的VBX和杂原子(S,O,N,
更新日期:2020-12-11
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