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The influence of feeding and gastroprotectant medications on the Factor Xa inhibitory activity of orally administered rivaroxaban in normal dogs
Journal of Veterinary Emergency and Critical Care ( IF 1.3 ) Pub Date : 2020-10-27 , DOI: 10.1111/vec.13019 Alex M. Lynch 1 , Laura K. Ruterbories 1 , Emily Griffith 2 , Rita M. Hanel 3 , Alyssa P. Stablein 4 , Marjory B. Brooks 4
Journal of Veterinary Emergency and Critical Care ( IF 1.3 ) Pub Date : 2020-10-27 , DOI: 10.1111/vec.13019 Alex M. Lynch 1 , Laura K. Ruterbories 1 , Emily Griffith 2 , Rita M. Hanel 3 , Alyssa P. Stablein 4 , Marjory B. Brooks 4
Affiliation
Rivaroxaban is a new anticoagulant option for dogs, yet its reported oral bioavailability is as low as 60%. The objective of this study was to examine the influence of feeding and gastroprotectant medications on the bioactivity (anti‐Xa activity) of rivaroxaban in healthy dogs.
中文翻译：
喂养和胃肠道保护药物对正常犬口服利伐沙班的Xa因子抑制活性的影响
利伐沙班是一种新的抗凝剂，但据报道其口服生物利用度低至60％。这项研究的目的是检查饲喂和胃保护药物对健康狗中利伐沙班生物活性（抗Xa活性）的影响。
更新日期：2020-10-27
中文翻译：
喂养和胃肠道保护药物对正常犬口服利伐沙班的Xa因子抑制活性的影响
利伐沙班是一种新的抗凝剂，但据报道其口服生物利用度低至60％。这项研究的目的是检查饲喂和胃保护药物对健康狗中利伐沙班生物活性（抗Xa活性）的影响。
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