Accumulating evidence shows that patients with anorexia nervosa (AN) have globally reduced brain mass, including lower cortical volume and thickness, which largely normalizes following weight restoration. The underlying mechanisms for these processes are unknown, and how age and severity of emaciation are associated with brain morphology in AN is poorly understood. We investigated associations of age, body mass index (BMI) and biochemical parameters with brain morphology among patients in treatment.

中文翻译：

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神经性厌食症患者年龄、体重指数、生化指标与脑形态的相关性

越来越多的证据表明，神经性厌食症 (AN) 患者的大脑质量整体减少，包括皮质体积和厚度降低，这在体重恢复后基本恢复正常。这些过程的潜在机制尚不清楚，而且人们对年龄和消瘦严重程度与 AN 大脑形态的关系知之甚少。我们调查了接受治疗的患者的年龄、体重指数 (BMI) 和生化参数与大脑形态的关联。