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Raman spectroscopy and gas chromatography with flame ionization detection as analysis tools in stability tests of selected synthetic psychoactive substances: 5-IT, MT-45 and 4-CMC
Vibrational Spectroscopy ( IF 2.5 ) Pub Date : 2020-11-01 , DOI: 10.1016/j.vibspec.2020.103176
Oliwia Frączak , Kinga Kądzioła-Długołęcka , Ilona Kijewska , Radosław Wilczek , Beata Tkacz-Szczęsna , Krzysztof Makowski , Piotr Komorowski , Robert Bachliński , Anna Trynda , Bogdan Walkowiak

Abstract This publication deals with three psychoactive substances: 5-IT (1-(1H-Indol-5-yl)propan-2-amine), MT-45 (1-cyclohexyl-4-(1,2-diphenylethyl)-piperazine) and 4-CMC (2-methylamino-1-para-chlorofluorophenyl-propan-1-one). These compounds are hazardous to the health of their users. They may be unstable during long and improper storage, which creates an additional risk for people who use them. Therefore, it is important to check whether this phenomenon occurs in case of these compounds. Syntheses of compounds were carried out in our laboratory. Their identity was confirmed using a wide range of spectrometric, spectroscopic and chromatographic methods. Raman spectroscopy and gas chromatography with flame ionization detection were used as analysis tools in stability tests. The impact of storage time (up to 3 months) and temperature conditions (−20 °C, +4 °C, RT, +40 °C) on samples was examined.

中文翻译:

拉曼光谱和气相色谱与火焰电离检测作为选定合成精神活性物质稳定性测试的分析工具:5-IT、MT-45 和 4-CMC

摘要 本出版物涉及三种精神活性物质:5-IT (1-(1H-Indol-5-yl)propan-2-amine)、MT-45 (1-cyclohexyl-4-(1,2-diphenylethyl)-piperazine ) 和 4-CMC (2-methylamino-1-para-chlorofluorophenyl-propan-1-one)。这些化合物对其使用者的健康有害。它们在长期和不当储存期间可能会不稳定,这给使用它们的人带来了额外的风险。因此,重要的是检查这些化合物是否会发生这种现象。化合物的合成在我们的实验室进行。使用范围广泛的光谱、光谱和色谱方法确认了它们的身份。拉曼光谱和带有火焰电离检测的气相色谱被用作稳定性测试的分析工具。
更新日期:2020-11-01
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