Abstract Kashmir Merino is the fine wool breed developed from cross of native sheep breeds of Kashmir valley (India) and Delain Merino rams (USA). This new breed is very popular in the temperate Himalayan region of Kashmir, for wool and mutton production, thereby contributing significantly to the economy of local farmers. We determined seroprevalence and associated risk factor of Mycobacterium avium subspecies paratuberculosis(MAP) in the flocks of Kashmir Merino sheep. A total of 450 serum samples were collected from13 villages over a period of 13 months (June, 2016 - July, 2017) using stratified random sampling. Samples were screened for MAP antibodies by ‘indigenous ELISA kit’ (i_ELISA kit). Data related to the flock and management risk factors was collected from individual farmers during sampling. Apparent and true seroprevalence was 43.3% (40.99-45.66at 95% confidence interval) and 73.8% (71.81-75.9 at 95% confidence interval), respectively. Of 25 flocks screened,17 were positive for MAP(68.0%, 72.0 -88.0% at 95% confidence interval) and all villages had MAP positive flocks. Villages selected for the study had apparent sero-prevalence between 40.0% (31.0-48.9% at 95% confidence interval) and 46.6% (36.9-55.0% at 95% confidence interval), and the difference was non-significant (P > 0.05). Chi square and odds ratio analysis of risk factors revealed significant (P

中文翻译：

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鸟分枝杆菌亚种血清阳性率和危险因素分析的横断面研究。印度中央克什米尔山谷克什米尔美利奴羊群的副结核病

摘要 克什米尔美利奴羊是由克什米尔山谷（印度）和德兰美利奴公羊（美国）的本地绵羊品种杂交发展而来的细羊毛品种。这种新品种在克什米尔的喜马拉雅温带地区非常受欢迎，用于羊毛和羊肉生产，从而为当地农民的经济做出了重大贡献。我们确定了克什米尔美利奴羊群中鸟分枝杆菌副结核亚种 (MAP) 的血清阳性率和相关危险因素。使用分层随机抽样，在13个月（2016年6月-2017年7月）期间从13个村庄共收集了450份血清样本。通过“本土ELISA试剂盒”（i_ELISA试剂盒）筛选样品的MAP抗体。在抽样期间从个体养殖者那里收集与鸡群和管理风险因素相关的数据。表观和真实血清阳性率为 43.3% (40. 95% 置信区间为 99-45.66）和 73.8%（95% 置信区间为 71.81-75.9）。在筛选的 25 个鸡群中，有 17 个为 MAP 阳性（68.0%，95% 置信区间为 72.0 -88.0%），所有村庄都有 MAP 阳性鸡群。选择用于研究的村庄的血清阳性率在 40.0%（95% 置信区间为 31.0-48.9%）和 46.6%（95% 置信区间为 36.9-55.0%）之间，差异不显着（P > 0.05） ）。危险因素的卡方和优势比分析显示显着（P 9% 在 95% 置信区间）和 46.6%（在 95% 置信区间为 36.9-55.0%），差异不显着（P > 0.05）。危险因素的卡方和优势比分析显示显着（P 9% 在 95% 置信区间）和 46.6%（在 95% 置信区间为 36.9-55.0%），差异不显着（P > 0.05）。危险因素的卡方和优势比分析显示显着（P