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Polychromatic luminescence and improved antifungal performance of succinic acid in the lattice of L-Lysine monohydrochloride
Saudi Journal of Biological Sciences ( IF 4.4 ) Pub Date : 2020-10-24 , DOI: 10.1016/j.sjbs.2020.10.021
B. Aneeba , S.V. Ashvin Santhia , R. Sheela Christy , Fahad A. Al-Misned , Hamed A. El-Serehy , S. Vinu

The incorporation of succinic acid (SA) in the lattice of L-Lysine monohydrochloride (LM) has opened the new avenue in the field of production and application of scintillator materials such as LED and antifungal drug. Crystalline trait and monoclinic structure were scanned by XRD. The existence of carbonyl, carboxylate and protonated amine group were confirmed through FTIR and UV spectra predicted the transmittance of SA: LM crystal. Polychromatic luminescence behaviour had achieved through the incorporation of SA instead of blue luminescence, which is a new result. Also SA: LM exhibited good response towards pathogenic fungi which causes numerous types of infections and diseases in both humans and animals. The high inhibitory zone at 16 mm was formed by the grown SA: LM crystal against the life threatening fungi like Candida albicans. Also fungal inhibition against candida parapsilosis and Aspergillus flaves, respectively, were tuned by the inclusion of succinic acid.



中文翻译:

L-赖氨酸单盐酸盐晶格中琥珀酸的多色发光和改善的抗真菌性能

在L-赖氨酸单盐酸盐(LM)的晶格中掺入琥珀酸(SA),为闪烁体材料(如LED和抗真菌药)的生产和应用开辟了新途径。用XRD扫描结晶性和单斜晶结构。通过FTIR证实了羰基,羧酸根和质子化胺基的存在,紫外光谱预测了SA:LM晶体的透射率。通过掺入SA而不是蓝色发光实现了多色发光行为,这是新的结果。SA:LM对病原性真菌也表现出良好的反应性,这种病原性真菌会导致人类和动物的多种感染和疾病。通过生长的SA:LM晶体形成了16 mm的高抑制区白色念珠菌。还通过加入琥珀酸来调节分别对副念珠菌和曲霉菌的真菌抑制作用

更新日期:2020-12-25
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