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The power spectrum of the membrane voltage driven by a single nACh receptor
Journal of Theoretical Biology ( IF 2 ) Pub Date : 2020-10-22 , DOI: 10.1016/j.jtbi.2020.110528 Jia-Zeng Wang 1 , Ying-Tao Meng 1
中文翻译:
由单个nACh受体驱动的膜电压的功率谱
更新日期:2020-11-02
Journal of Theoretical Biology ( IF 2 ) Pub Date : 2020-10-22 , DOI: 10.1016/j.jtbi.2020.110528 Jia-Zeng Wang 1 , Ying-Tao Meng 1
Affiliation
Being the primary mean of translating the chemical signal into the electric signal in neuromuscular junction, the nACh receptor is the first kind of ligand-gated channel that its kinetic structure has been known clearly. The next problem is to know quantitatively how it works in a living system. In this paper, we construct a piece-wise deterministic process to mimic the membrane voltage fluctuation driven by a single nACh receptor. The power spectrum of the voltage fluctuation is solved analytically, which reveals the -type noise.
中文翻译:
由单个nACh受体驱动的膜电压的功率谱
nACh受体是将神经肌肉接头中的化学信号转化为电信号的主要手段,是第一类已知其动力学结构的配体门控通道。下一个问题是定量了解其在生命系统中的工作方式。在本文中,我们构建了一个分段确定性过程,以模拟由单个nACh受体驱动的膜电压波动。解析了电压波动的功率谱,揭示了型噪音。