Background

The incidence of acute pancreatitis (AP) is characterized by circannual and geographical variation. The aim of this study was to describe seasonal variation and trends in hospitalizations for AP in the USA with respect to AP etiology.

Methods

The Nationwide Inpatient Sample data (2000–2016) from the Healthcare Cost and Utilization Project were used. The study population included all primary hospitalizations for AP. Biliary AP (BAP) and alcohol-induced AP (AAP) were distinguished by diagnostic and procedural ICD codes. Seasonal trend decomposition was performed.

Results

There was a linear increase in annual incidence (per 100 000 population) of AAP in the USA (from 17.0 in 2000 to 22.9 in 2016), while incidence of BAP, equaled 19.9 in 2000, peaked at 22.1 in 2006 and decreased to 17.4 in 2016. AP incidence demonstrated 18% annual incidence amplitude with summer peak and winter trough, more prominent in AAP. In 2016, within AAP, the highest incidence (per 100 000 population) was noted among African-Americans (up to 50.4), followed by males aged 56–70 years (26.5) and Asians of low income (25.5); within BAP, above the average incidence was observed in Hispanic (up to 25.8) and Asian (up to 25.0) population. The most consistent and rapid increase in AP incidence was noted in males aged 56–70 years with an alcoholic etiology (average 6% annual incidence growth).

Conclusions

The incidence and annual trends of AP vary significantly among demographic and socioeconomic groups and this knowledge may be useful for the planning of healthcare resources and identification of at-risk populations.

中文翻译：

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美国急性酒精相关性和胆源性胰腺炎住院的趋势和季节性

背景

急性胰腺炎 (AP) 的发病率具有季节性和地域性变化特征。本研究的目的是根据 AP 病因描述美国 AP 住院的季节性变化和趋势。

方法

使用了来自医疗保健成本和利用项目的全国住院患者样本数据（2000-2016 年）。研究人群包括所有因 AP 住院的患者。胆道 AP (BAP) 和酒精诱发的 AP (AAP) 通过诊断和程序 ICD 代码进行区分。进行了季节性趋势分解。

结果

美国 AAP 的年发病率（每 10 万人口）呈线性增长（从 2000 年的 17.0 增加到 2016 年的 22.9），而 BAP 的发病率在 2000 年为 19.9，在 2006 年达到峰值 22.1，并下降到 17.4 2016. AP 发病率以每年 18% 的幅度增长，夏季高峰期和冬季低谷期，以 AAP 更为突出。2016 年，在 AAP 中，非洲裔美国人的发病率最高（每 10 万人）（高达 50.4），其次是 56-70 岁的男性（26.5）和低收入的亚洲人（25.5）；在 BAP 中，西班牙裔（高达 25.8）和亚洲（高达 25.0）人群的发病率高于平均水平。56-70 岁有酒精病因的男性中 AP 发病率的增长最为一致和迅速（平均每年发病率增长 6%）。

结论

AP 的发病率和年度趋势在人口和社会经济群体之间差异很大，这些知识可能有助于规划医疗资源和识别高危人群。