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Signatures of brain plasticity supporting language recovery after perinatal arterial ischemic stroke
Brain and Language ( IF 2.5 ) Pub Date : 2021-01-01 , DOI: 10.1016/j.bandl.2020.104880
Clément François 1 , Alfredo Garcia-Alix 2 , Laura Bosch 3 , Antoni Rodriguez-Fornells 4
Affiliation  

Brain imaging methods such as functional Magnetic Resonance Imaging (fMRI) and Diffusion Tensor Imaging (DTI) have already been used to decipher the functional and structural brain changes occurring during normal language development. However, little is known about the differentiation of the language network after an early lesion. While in adults, stroke over the left hemisphere generally induces post-stroke aphasia, it is not always the case when a stroke occurs in the perinatal period, thus revealing a remarkable plastic power of the language network during early development. In particular, the role of perilesional tissues, as opposed to undamaged brain areas in the functional recovery of language functions after an early insult, remains unclear. In this review article, we provide an overview of the extant literature using functional and structural neuroimaging data revealing the signatures of brain plasticity underlying near-normal language development.

中文翻译:

支持围产期动脉缺血性卒中后语言恢复的脑可塑性特征

脑成像方法,例如功能性磁共振成像 (fMRI) 和扩散张量成像 (DTI),已被用于破译正常语言发育过程中发生的功能性和结构性大脑变化。然而,关于早期病变后语言网络的分化知之甚少。虽然在成人中,左半球的中风通常会诱发中风后失语症,但在围产期发生中风的情况并不总是如此,因此在早期发育过程中,语言网络具有显着的可塑性。特别是,与未受损的大脑区域相反,在早期损伤后语言功能的功能恢复中,病灶周围组织的作用仍不清楚。在这篇评论文章中,
更新日期:2021-01-01
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