当前位置: X-MOL 学术Neurotherapeutics › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Treatment of Dystonia: Medications, Neurotoxins, Neuromodulation, and Rehabilitation
Neurotherapeutics ( IF 5.7 ) Pub Date : 2020-10-23 , DOI: 10.1007/s13311-020-00944-0
Ian O Bledsoe 1 , Aaron C Viser 1 , Marta San Luciano 1
Affiliation  

Dystonia is a complex disorder with numerous presentations occurring in isolation or in combination with other neurologic symptoms. Its treatment has been significantly improved with the advent of botulinum toxin and deep brain stimulation in recent years, though additional investigation is needed to further refine these interventions. Medications are of critical importance in forms of dopa-responsive dystonia but can be beneficial in other forms of dystonia as well. Many different rehabilitative paradigms have been studied with variable benefit. There is growing interest in noninvasive stimulation as a potential treatment, but with limited long-term benefit shown to date, and additional research is needed. This article reviews existing evidence for treatments from each of these categories. To date, there are many examples of incomplete response to available treatments, and improved therapies are needed.



中文翻译:

肌张力障碍的治疗:药物、神经毒素、神经调节和康复

肌张力障碍是一种复杂的疾病,具有许多单独发生或与其他神经系统症状组合发生的表现。近年来,随着肉毒杆菌毒素和脑深部刺激的出现,其治疗得到了显着改善,但还需要进一步研究以进一步完善这些干预措施。药物对多巴反应性肌张力障碍的形式至关重要,但对其他形式的肌张力障碍也有益。已经研究了许多不同的康复范例,并具有不同的益处。人们对无创刺激作为一种潜在的治疗方法越来越感兴趣,但迄今为止显示的长期益处有限,还需要进一步的研究。本文回顾了这些类别中每一种治疗的现有证据。迄今为止,

更新日期:2020-10-30
down
wechat
bug