• A polarized-macrophages-based drug delivery system (M1/SLNP) was presented for the cell-chemotherapy of cancer.

• Polarized-macrophages were used both as therapeutic tool to provide immunotherapy and as delivery vessel to target deliver chemotherapeutic drugs to tumor tissues for chemotherapy simultaneously.

• M1/SLNP was a multifunctional delivery system with simple structure, excellent safety, and without complex synthesis process.

中文翻译：

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用于增强肿瘤靶向和细胞化疗的纳米粒子负载极化巨噬细胞

• 提出了一种基于极化巨噬细胞的药物递送系统 (M1/SLNP) 用于癌症的细胞化疗。

• 极化巨噬细胞既可用作提供免疫治疗的治疗工具，也可用作递送容器以同时将化疗药物靶向递送至肿瘤组织以进行化疗。

• M1/SLNP是一种结构简单、安全性好、合成过程不复杂的多功能递送系统。