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Cytogenetic follow-up of an individual after accidental exposure to industrial radiation using dicentric frequency in blood lymphocytes
Mutation Research/Genetic Toxicology and Environmental Mutagenesis ( IF 1.9 ) Pub Date : 2020-10-22 , DOI: 10.1016/j.mrgentox.2020.503276
İnci Güçlü 1
Affiliation  

A radiation accident occurred in Bursa, Turkey, in July 2005. An industrial radiographer was exposed to industrial iridium-192 gamma rays for 5 h while laying the natural gas line. After 5 h, the victim had a break because of vomiting and nausea. He ended his work, considering that he might have been exposed to radiation.

In a few days, erythema, pain, desquamation, edema started in both hands of the victim. The biological dose assessment was started based on frequencies of dicentrics and rings in peripheral blood lymphocytes ten days after the radiation accident. 6 repeated blood samples were taken for 9 years and analyzed staining after giemsa. After 9 years, decline at dicentric frequencies is significant, but still, dicentric contain cells were detected, which were a strong indicator for external radiation exposure.



中文翻译:

使用血液淋巴细胞双着丝频率对意外暴露于工业辐射后的个体进行细胞遗传学随访

2005 年 7 月,土耳其布尔萨发生了一起辐射事故。一名工业射线照相师在铺设天然气管线时暴露于工业铱 192 伽马射线 5 小时。5小时后,受害者因呕吐和恶心而休息。他结束了他的工作,考虑到他可能已经暴露在辐射中。

几天后,受害者双手开始出现红斑、疼痛、脱皮、水肿。根据辐射事故后 10 天外周血淋巴细胞中双着丝粒和环的频率开始生物剂量评估。9 年内重复采集 6 份血样,并在 giemsa 后分析染色。9 年后,双着丝粒频率显着下降,但仍检测到含有双着丝粒的细胞,这是外部辐射暴露的强指标。

更新日期:2020-11-09
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