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GC-FID-MS and X-ray Diffraction for the Detailed Evaluation of the Volatiles From Senecio filaginoides
Natural Product Communications ( IF 1.8 ) Pub Date : 2020-10-27 , DOI: 10.1177/1934578x20968443
Catalina M. van Baren 1 , Silvia B. González 2 , Arnaldo L. Bandoni 1 , Paola Di Leo Lira 1, 3 , María A. Bucio 4 , Angelina Hernández-Barragán 4 , Pedro Joseph-Nathan 4
Affiliation  

The medicinal aromatic plant Senecio filaginoides DC, which is very widespread in the Patagonia region, was harvested at the vegetative, flowering, and fructification stages. The materials were extracted by hydrodistillation, yielding in average 0.34% v/w of essential oils with a pleasant sweet and greenish scent. A total of 56 components were identified by gas chromatography using flame ionization detection and mass spectra measurements, representing 96.1%-97.6% of the total oil. The sesquiterpenoid 10αH-furanoeremophil-1-one (1) appeared as a major constituent (16.2%-26.9%) of the oil. It could be isolated by cooling the oil at 4°C, thus yielding yellow crystalline solids. Its stereochemistry was assigned by single-crystal X-ray diffraction since previous studies identified the compound with different stereochemistries. The use of classical separation and analytical methodologies remains as a very useful strategy for the correct identification of compounds present in the volatile fraction of a plant and is a route for potential industrial applications.



中文翻译:

GC-FID-MS和X射线衍射用于详细评估千里光的挥发

在巴塔哥尼亚地区非常普遍的药用芳香植物Senecio filaginoides DC是在营养,开花和果实形成阶段收获的。通过加氢蒸馏来提取原料,平均产生0.34%v / w的香精油,并带有宜人的甜和绿色气味。通过使用火焰离子化检测和质谱测量的气相色谱法鉴定出总共56种成分,占总油量的96.1%-97.6%。所述倍半萜10 αH -furanoeremophil -1-酮(1)似乎是油的主要成分(16.2%-26.9%)。可以通过将油冷却至4°C进行分离,从而生成黄色结晶固体。由于先前的研究发现该化合物具有不同的立体化学,因此它的立体化学通过单晶X射线衍射确定。使用经典的分离和分析方法仍然是正确鉴定植物挥发性成分中化合物的非常有用的策略,并且是潜在的工业应用途径。

更新日期:2020-10-29
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