Background Studies examining the effects of therapeutic interventions after stroke often focus on changes in loss of body function/structure (impairment). However, improvements in activities limitations and participation restriction are often higher patient priorities, and the relationship that these measures have with loss of body function/structure is unclear. Objective This study measured gains across WHO International Classification of Function (ICF) dimensions and examined their interrelationships. Methods Subjects were recruited 11 to 26 weeks after hemiparetic stroke. Over a 3-week period, subjects received 12 sessions of intensive robot-based therapy targeting the distal arm. Each subject was assessed at baseline and at 1 month after end of therapy. Results At baseline, subjects (n = 40) were 134.7 ± 32.4 (mean ± SD) days poststroke and had moderate-severe arm motor deficits (arm motor Fugl-Meyer score of 35.6 ± 14.4) that were stable. Subjects averaged 2579 thumb movements and 1298 wrist movements per treatment session. After robot therapy, there was significant improvement in measures of body function/structure (Fugl-Meyer score) and activity limitations (Action Research Arm Test, Barthel Index, and Stroke Impact Scale–Hand), but not participation restriction (Stroke Specific Quality of Life Scale). Furthermore, while the degree of improvement in loss of body function/structure was correlated with improvement in activity limitations, neither improvement in loss of body function/structure nor improvement in activity limitations was correlated with change in participation restriction. Conclusions After a 3-week course of robotic therapy, there was improvement in body function/structure and activity limitations but no reduction in participation restriction.

中文翻译：

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卒中患者接受机器人治疗后，WHO 各方面功能的获益

检查中风后治疗干预效果的背景研究通常侧重于身体功能/结构丧失（损伤）的变化。然而，活动限制和参与限制的改善通常是患者优先考虑的事项，并且这些措施与身体功能/结构丧失的关系尚不清楚。目标 本研究衡量了世卫组织国际功能分类 (ICF) 维度的收益，并检查了它们之间的相互关系。方法 在偏瘫性卒中后 11 至 26 周招募受试者。在 3 周的时间里，受试者接受了 12 次针对远端手臂的强化机器人治疗。在基线和治疗结束后 1 个月对每位受试者进行评估。结果 在基线时，受试者 (n = 40) 为 134.7 ± 32。中风后 4（平均值±标准差）天，并且有稳定的中重度手臂运动缺陷（手臂运动 Fugl-Meyer 评分为 35.6±14.4）。受试者在每次治疗期间平均进行 2579 次拇指运动和 1298 次腕部运动。机器人治疗后，身体功能/结构（Fugl-Meyer 评分）和活动限制（行动研究手臂测试、Barthel 指数和中风影响量表-手）的测量有显着改善，但参与限制（中风特定质量生命量表）。此外，虽然身体功能/结构丧失的改善程度与活动限制的改善相关，但身体功能/结构丧失的改善和活动限制的改善都与参与限制的变化无关。结论 经过 3 周的机器人治疗疗程后，