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Identifying environmental risk factors and gene–environment interactions in holoprosencephaly
Birth Defects Research ( IF 2.1 ) Pub Date : 2020-10-28 , DOI: 10.1002/bdr2.1834
Yonit A Addissie 1 , Angela Troia 2 , Zoe C Wong 2 , Joshua L Everson 3, 4 , Beth A Kozel 2 , Maximilian Muenke 1 , Robert J Lipinski 3, 4 , Kristen M C Malecki 4, 5 , Paul Kruszka 1
Affiliation  

Holoprosencephaly is the most common malformation of the forebrain (1 in 250 embryos) with severe consequences for fetal and child development. This study evaluates nongenetic factors associated with holoprosencephaly risk, severity, and gene–environment interactions.

中文翻译:

识别全前脑畸形的环境风险因素和基因-环境相互作用

Holoprosencephaly 是最常见的前脑畸形(250 个胚胎中有 1 个),对胎儿和儿童发育具有严重后果。本研究评估了与前脑全畸形风险、严重程度和基因-环境相互作用相关的非遗传因素。
更新日期:2021-01-04
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