Oral surgery has undergone dramatic developments in recent years due to the use of biomaterials. The aim of the present review is to provide a general overview of the current biomaterials used in oral surgery and to comprehensively outline their impact on post-operative wound healing. A search in Medline was performed, including hand searching. Combinations of searching terms and several criteria were applied for study identification, selection, and inclusion. The literature was searched for reviews published up to July 2020. Reviews evaluating the clinical and histological effects of biomaterials on post-operative wound healing in oral surgical procedures were included. Review selection was performed by two independent reviewers. Disagreements were resolved by a third reviewer, and 41 reviews were included in the final selection. The selected papers covered a wide range of biomaterials such as stem cells, bone grafts, and growth factors. Bioengineering and biomaterials development represent one of the most promising perspectives for the future of oral surgery. In particular, stem cells and growth factors are polarizing the focus of this ever-evolving field, continuously improving standard surgical techniques, and granting access to new approaches.

中文翻译：

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生物材料在口腔外科伤口愈合中的临床前和临床应用：综述综述

近年来，由于使用生物材料，口腔外科发生了巨大的发展。本综述的目的是提供用于口腔外科手术的当前生物材料的一般概述，并全面概述其对术后伤口愈合的影响。在Medline中进行了搜索，包括手工搜索。搜索词和几种标准的组合应用于研究的识别，选择和纳入。从文献中检索到2020年7月为止发表的评论。包括评价生物材料在口腔外科手术中对术后伤口愈合的临床和组织学影响的评论。评审选择由两名独立评审进行。分歧由第三位审阅者解决，最终选择中包括41条审阅。入选的论文涵盖了广泛的生物材料，例如干细胞，骨移植物和生长因子。生物工程和生物材料的发展代表了口腔外科未来的最有前景的前景之一。特别是，干细胞和生长因子正在使这个不断发展的领域成为人们关注的焦点，不断改进标准的外科手术技术，并获得了使用新方法的途径。