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Current Understanding of the Role of Frailty in Cardiovascular Disease
Circulation Journal ( IF 3.3 ) Pub Date : 2020-10-23 , DOI: 10.1253/circj.cj-20-0594
Yoshihiro Uchikado 1 , Yoshiyuki Ikeda 1 , Mitsuru Ohishi 1
Affiliation  

The elderly population is increasing because of increasing life expectancy, and the prevalence of frailty increases with age. Frailty commonly coexists with cardiovascular diseases (CVDs), such as coronary artery disease (CAD), heart failure (HF), aortic stenosis (AS), and atrial fibrillation (AF). Frail patients who undergo revascularization for CAD have higher complication rates; those with HF have a high prevalence of poor outcomes, and those with AF are vulnerable to increased stroke incidence. Moreover, frailty and asymptomatic severe AS were independent factors for mortality. The presence of frailty can lead to poor clinical outcomes, and frailty has been identified as a risk factor for mortality. Thus, the identification of frail patients who are at higher risks of disability and adverse clinical outcomes is important. In this review, the relationship between frailty and CVD is appraised and optimal treatments for frail patients are discussed.



中文翻译:

当前对衰弱在心血管疾病中作用的理解

由于预期寿命的增加,老年人口正在增加,并且虚弱的患病率随着年龄的增长而增加。虚弱通常与心血管疾病 (CVD) 共存,例如冠状动脉疾病 (CAD)、心力衰竭 (HF)、主动脉瓣狭窄 (AS) 和心房颤动 (AF)。接受 CAD 血运重建术的虚弱患者并发症发生率较高;HF 患者预后不良的发生率很高,而 AF 患者容易增加卒中发生率。此外,虚弱和无症状的严重 AS 是死亡率的独立因素。虚弱的存在会导致不良的临床结果,虚弱已被确定为死亡的危险因素。因此,识别具有较高残疾风险和不良临床结果的虚弱患者很重要。在这次审查中,

更新日期:2020-10-28
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