Photoacoustic imaging (PAI) is often performed simultaneously with ultrasound imaging and can provide functional and cellular information regarding the tissues in the anatomical markers of the imaging. This paper describes in detail the basic principles of photoacoustic/ultrasound (PA/US) imaging and its application in recent years. It includes near-infrared-region PA, photothermal, photodynamic, and multimode imaging techniques. Particular attention is given to the relationship between PAI and ultrasonic imaging; the latest high-frequency PA/US imaging of small animals, which involves not only B-mode, but also color Doppler mode, power Doppler mode, and nonlinear imaging mode; the ultrasonic model combined with PAI, including the formation of multimodal imaging; the preclinical imaging methods; and the most effective detection methods for clinical research for the future.

中文翻译：

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多峰超声引导光声成像技术应用的最新进展

光声成像（PAI）通常与超声成像同时进行，可以提供有关成像解剖标记中组织的功能和细胞信息。本文详细介绍了光声/超声（PA / US）成像的基本原理及其近年来的应用。它包括近红外区PA，光热，光动力和多模成像技术。特别注意PAI和超声成像之间的关系。最新的小动物高频PA / US成像，不仅涉及B模式，还涉及彩色多普勒模式，功率多普勒模式和非线性成像模式；与PAI结合的超声模型，包括多模态成像的形成；临床前成像方法；