Fenoxycarb 0-ethyl N-(2-(4-pheoxyphenoxy)-ethyl) carbamate is the most potent juvenile hormone analogue against a variety of insect species including the silkworm Bombyx mori. In this study, the effects of fenoxycarb on silkworm Bombyx mori brain neurosecretory cells in 5th instar were investigated. Fenoxycarb (1 ng/10 µl) was applied topically along the dorsa-medial line to the animals in the spinning behavior on day 1 of the experimental group. Brains removed by dissection were histologically examined by hematoxylin eosin (hem&eosin) and paraldehyde fuchsin staining. Three types of neurosecretory cells (NSCs) were identified, NSC-1, NSC-2 and NSC-3. It was determined that cell secretions were in different density on different days. It was shown that the secretion density of cells on different days was not the same as the experimental and control groups. The fenoxycarb was found to suppress the bombyxin (insulin-like peptides) secretion of cells in the spinning behavior on day 2. Also, it stimulated the division of NSCs on the spinning behavior on day 5.

Fenoxycarb 0-ethyl N-(2-(4-pheoxyphenoxy)-ethyl)carbamate 是对包括家蚕Bombyx mori在内的多种昆虫物种最有效的保幼激素类似物。本研究中苯氧威对家蚕家蚕的影响研究了5龄的脑神经分泌细胞。在实验组的第 1 天，将 Fenoxycarb（1 ng/10 µl）沿背中线局部应用于处于纺纱行为的动物。通过解剖取出的大脑通过苏木精伊红（hem&eosin）和三聚乙醛品红染色进行组织学检查。确定了三种类型的神经分泌细胞 (NSC)，即 NSC-1、NSC-2 和 NSC-3。确定不同天数的细胞分泌物密度不同。结果表明，不同天的细胞分泌密度与实验组和对照组不同。发现 fenoxycarb 在第 2 天的旋转行为中抑制细胞分泌的蜂巢蛋白（胰岛素样肽）。此外，它在第 5 天的旋转行为中刺激了 NSC 的分裂。