Chitosan has various merits including antimicrobial activity but shows poor liquid handling properties such as fluid absorption and retention, keeping moisture environment, and gel-formation. In order to improve the characteristics of chitosan nonwovens as a wound dressing material, carboxymethyl chitosan nonwovens were prepared by direct carboxymethylation reaction of needle-punched chitosan nonwovens. FT-IR and degree of deacetylation analysis showed O-substitution was dominant, and the amount of sodium chloroacetate and sodium hydroxide had effects on degree of substitution. As the degree of substitution increased, fluid absorption capacities, fluid retention capacities, wet dimensional stability, and tensile strength were increased. Liquid spreading and moisture evaporation were suppressed with the increase of degree of substitution. Overall, O-carboxymethyl chitosan has good potential as a moist wound dressing material.

壳聚糖具有多种优点，包括抗微生物活性，但显示出较差的液体处理性能，例如液体吸收和保留，保持水分环境以及形成凝胶。为了改善壳聚糖无纺布作为伤口敷料的特性，通过针刺壳聚糖无纺布的直接羧甲基化反应制备了羧甲基壳聚糖无纺布。FT-IR和脱乙酰度分析表明O-取代占主导，氯乙酸钠和氢氧化钠的量对取代度有影响。随着取代度的增加，流体吸收能力，流体保持能力，湿尺寸稳定性和拉伸强度增加。随着取代度的增加，液体扩散和水分蒸发得到抑制。总体，